Proteins and peptides are the primary functional polymers of medical biochemistry, directing virtually all cellular processes through their structural diversity, catalytic activities and signalling ...

The genetic code has given rise to the enormous diversity of proteins we see in nature—and rearranging the order of codons that make up a protein’s sequence leads to an immense variety of structure ...

New AI‑designed miniproteins precisely modulate GPCR signaling and reveal a new screening system for targeting receptors long ...

A pink ribosome surrounds part of a red-and-yellow helix-shaped strand of messenger RNA while a yellow protein branch extends from the ribosome. A graphic representation of a ribosome (pink) ...

G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a ...

Amyloids are perhaps best known as a key driver of Alzheimer’s disease. The amorphous proteins, found throughout the human body, stick to nerve cells like plaque, choking off their function and ...

For those outside the chemistry cognoscenti, the announcement might have seemed little more than researchers patting each other on the back. But the question of protein folding had plagued scientists ...

G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a ...

In every organism, the regulation of cell populations is a constant process. This balance relies on a continuous interplay ...

In Greek mythology, Proteus, son of Poseidon and prophetic shepherd of sea-beasts, could foretell the future. The elusive sea god was difficult to capture as he assumed many forms—a lion, a serpent, ...

Proteins and peptides form the cornerstone of cellular function, serving not only as essential catalysts and structural components but also as mediators of signalling and regulation in health and ...