In this study, we used a combination of the MEK inhibitor PD184352 with BMS-214662 to increase the effect of BMS-214662 in a CML blast crisis cell line, K562 and in primary CP CML stem/progenitor ...
Using the newborn NOD/SCID/IL2rγ null xenotransplantation model, we demonstrate that CD34+CD38+CD19+ cells as well as CD34+CD38−CD19+ cells have the capacities to initiate B-ALL, to infiltrate into ...
Age and serum lactate dehydrogenase level are independent prognostic factors in human immunodeficiency virus-related non-Hodgkin's lymphomas: a single-institute study of 96 patients. The objective of ...
Expanding on the Cooperative Center of Excellence in Hematology (CCEH) at Fred Hutchinson Cancer Center’s expertise in providing Human CD34+ HSPCs, we have established a high-efficiency and ...
Polycythemia vera is the ultimate phenotypic consequence of the V617F mutation in Janus kinase 2 (encoded by JAK2), but the extent to which this mutation influences the behavior of the involved CD34+ ...
Detection of the t(14;18) chromosomal translocation by interphase cytogenetics with yeast-artificial-chromosome probes in follicular lymphoma and nonneoplastic lymphoproliferation. The median WBC and ...
Here, we describe the first two patients, one with TDT and the other with SCD, who were infused with CTX001 (autologous CRISPR-Cas9–edited CD34+ HSPCs that were genetically edited to reactivate the ...
SEOUL, South Korea, April 24, 2026 /PRNewswire/ -- Miracell, a stem cell-focused biotechnology company, announced that clinical results have demonstrated significant cognitive improvement and ...
Study published in SCIE-indexed international journal Molecular Neurobiology Three intravenous infusions at four-week intervals showed benefits in cognition, brain metabolism, and structural ...
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