While scientists have known for more than two decades that all cells use a strategy called RNA interference to regulate gene ...

Chinese hamster ovary (CHO) cell lines are one of the most-used cell-based protein expression systems for therapeutics, thanks to their ability to support post-translational modifications such as ...

Blood does more than move oxygen and fight infection. It also carries a record of where animals came from. A new evolutionary ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

Li believes cells sometimes purposely select transcripts doomed for NMD to decrease expression levels. If the nascent RNA is destroyed before it gets fully transcribed, it will never produce proteins ...

Expression of the clusterin gene in hematopoietic stem cells marks an age-related shift toward myeloid/platelet over lymphoid cell production In recent years, there has been a growing trend of an ...

Single B cell platforms have emerged as powerful tools for antibody discovery, enabling the rapid isolation and screening of ...

Optimizing key steps of Southern blotting analysis for detecting transgene integration sites and assessing transgene integrity in Chinese hamster ovary (CHO) cell lines derived from transposon-based ...

Stem cells are the original cell type from which all other cells and tissues in the body develop through a very tightly regulated process. However, how stem cells differentiate in addition to ...