A protein thought to play a supporting role in DNA replication actually facilitates the whole process

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...
The Scientist

DNA Polymerase Works in Short Bursts Rather than One Long Stretch

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...
Nanowerk

Base Pair: The Building Blocks of DNA and RNA

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...
RMD Open

RA-risk synovium exhibits DNA damage coupled with impaired DNA repair in fibroblasts

Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...

Super-enhancers in cancer cells trigger DNA breaks and error-prone repair cycles

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...