Researchers describe a new way by which cells adapt to the aging process: by actively remodeling the endoplasmic reticulum, ...

DJ-1 is a protein with wide subcellular distribution and pleiotropic functions. The loss-of-function mutations of DJ-1 are associated with autosomal recessive early-onset Parkinson's disease yet the ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy ...

A fat signaling system controls the interface of cellular endoplasmic reticulum (ER) with early endosomes to regulate the shape and activity of mitochondria, and allow cells to survive periods of ...

Alexander Chernorudskiy, Ersilia Varone, Sara Francesca Colombo, Stefano Fumagalli, Alfredo Cagnotto, Angela Cattaneo, Mickael Briens, Mireille Baltzinger, Lauriane ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these ...