Schematic diagram of creating artificial enzyme-mimicking nanopockets in zirconium terephthalate UiO-66 for transfer hydrogenation of alkyl levulinates towards gamma-valerolactone. Credit: Tang ...
The snapshots reveal key reactions steps. At 0 ms, water molecules occupy the substrate-binding site. At 50 ms, a substrate-cofactor intermediate forms. At 100 ms, the product is released, and the ...
Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was published in Nature Communications. Subscribe to our newsletter for the ...