A new scientific focus on extrachromosomal circular DNA (eccDNA) is opening transformative possibilities for disease ...

An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes—known as extrachromosomal DNA, or ecDNA—can drive the growth of a large proportion of ...

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. The poor prognosis is due in part both to late detection and the cancer’s capacity to adapt and ...

Immunofluorescence images showing that cells with higher levels of the cancer-promoting MYC protein (red) also tend to exhibit high levels of DNA damage (green), suggesting that too much MYC leads to ...

A schematic describing what Inocles do and where they’re found. It shows the kinds of roles its genes might have, and how those jobs could be connected to things happening in the human body.

An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes – known as extrachromosomal DNA, or ecDNA – can drive the growth of a large proportion of ...