Luminescence and fluorescence-based assay methods prevail in modern HTS. Although invaluable as technologies, the problem of compound-related assay interferences such as quenching, auto-fluorescence, ...

The core mechanism involves labeling a target molecule, substrate, or probe with a fluorophore. Upon excitation, the fluorophore emits a signal that is proportional to the presence or activity of the ...

Efficient screening strategies are essential for identifying and advancing promising compounds across drug discovery ...

Fluorescent dyes are tools used throughout biotechnology and medicine that offer a unique method of detecting and quantifying the presence of a target molecule, cell, or tissue within an even more ...

Modern bioassays tend to fall under three common modalities: colorimetric, luminometric or fluorometric. Colorimetric assays record the amount of light absorbed by a reporter compound. This absorbance ...

Biotium, a leading developer of fluorescent reagents for life science research, announces the launch of the RNaseReveal™ Activity Assay Kit, with unparalleled sensitivity to detect RNase contamination ...

The latest advances in genome sequencing indicate proteases occur naturally in all organisms and account for about 2% of the human genome and 1–5% of genomes of infectious organisms. The human genome ...