MPN-BP transformation is driven by sequential mutations disrupting genomic stability, with TP53 mutations being strong predictors of progression. TP53 mutations confer a selective growth advantage, ...

It is often assumed that modern humans are no longer evolving. But there is now considerable agreement among scientists that evolution is still affecting our species—and this process is taking place ...

Researchers at the University of Maine are theorizing that human beings may be in the midst of a major evolutionary shift—driven not by genes, but by culture. "Human evolution seems to be changing ...

Researchers at the University of Maine are theorizing that human beings may be in the midst of a major evolutionary shift — driven not by genes, but by culture. In a paper published in the Oxford ...

A new Yale study provides a fuller picture of the genetic changes that shaped the evolution of the human brain, and how the process differed from the evolution of chimpanzees. For the study, published ...

The present theory offers a unified solution to three closely related evolutionary problems. (1) Why does an evolving population explore only a small fraction of the accessible pathways in genotype ...

MILAN — Is chronic lymphocytic leukemia (CLL) progression primarily driven by genetic mutations or by external cues from the tumor microenvironment? Despite major strides in targeted therapies, CLL ...

There are a variety of methods that have been established to curtail the spread of infectious disease, from isolation or donning of PPE to prevent human-to-human transmission, to culling infected ...

For over a thousand years, the story of human evolution was simple: Homo sapiens developed in Africa between 200,000 and 300,000 years ago from a single line of forebears. But today, one research has ...

Modern humans descended from not one, but at least two ancestral populations that drifted apart and later reconnected, long before modern humans spread across the globe. Using advanced analysis based ...