A neural circuit hidden in an understudied region of the brain plays a critical role in turning temporary pain into pain that ...

New research suggests pain is not a simple signal of injury but a process that unfolds across nerves, spinal cord, and brain.

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Chronic pain affects more than 50 million Americans, yet for decades, treatment options for pain that persists in the absence ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Around one million people every year suffer from a parasitic condition known as cutaneous leishmaniasis. Spread by sandfly bites, the parasite causes nasty skin ulcerations but for many people the ...

Three floors below Dmitriy Sheyn’s lab at Cedars-Sinai Medical Center, doctors remove degenerated intervertebral discs from patients with severe back pain. Instead of tossing the old discs, however, ...

Adolescents who report pain at the age of 18 are at higher risk of later self-harm. This is shown by a new study from Karolinska Institutet, published ...

The American College of Cardiology (ACC) expert decision pathway for chest pain can safely and effectively rule out acute coronary syndromes in most patients, but not for those with known coronary ...