In a new draft guidance issued on January 14, 2026, the FDA discussed the use of a modern statistical methodology in clinical trials designed to ...

High-dimensional -omics data such as genomic, transcriptomic, and metabolomic data offer great promise in advancing precision medicine. In particular, such data have enabled the investigation of ...

Although population association studies are not new, there remain many areas of disagreement over appropriate statistical analyses. This article provides an overview of statistical methods, including ...

A relatively simple statistical analysis method can more accurately predict the risk of landslides caused by heavy rain, according to a study coordinated by Brazilian researchers affiliated with the ...

The product development lifecycle is long and challenging. Whether it is translational research or clinical research, there are numerous obstacles in the design and management of a study and ...

Here we offer a 'meta-methodology' and framework in which to evaluate epistemological foundations of proposed statistical methods. On the basis of this framework, we consider that many statistical ...

Statistical methods now being used in adaptive biomarker-driven clinical trials are reviewed. Some previous paradigms for clinical trial design can limit the development of more effective methods on ...

Rand Wilcox does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...

The Center for Statistics and Advanced Analytics provides support to Boston College researchers related to the collection and the analysis of data. Our team includes statisticians and other data ...