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Fertilization occurs when egg and sperm meet, often while the egg is still in the fallopian tube. The first sperm to reach the egg in the fallopian tube binds to its surface, releasing enzymes from the acrosome surrounding its head that help it to break through the egg’s protective coating. The egg responds by releasing its own enzymes to ...
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Whether in vivo (in the body) or during IVF (in vitro fertilization), it takes the actions of many sp erm to achieve fertilization of the egg. The egg is surrounded by cumulus cells, which surrounded the egg while it was inside its follicle in the ovary. The sperm release an enzyme that breaks the bonds between these cells to help “clear a path” to the egg. Once some sp erm reach the egg, they release enzymes that help them break through the egg’s shell (zona pellucida). Though many sp erm try t
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